This volume contains the proceedings of the 10th International Conference on Veri?cation, Model Checking, and Abstract Interpretation (VMCAI 2009), held in Savannah, Georgia, USA, January 18-20, 2009. VMCAI 2009 was the 10th in a series of meetings. Previous meetings were heldinPortJe?erson1997, Pisa1998, Venice2002, NewYork2003, Venice2004, Paris 2005, Charleston 2006, Nice 2007, and San Francisco 2008. VMCAI centers on state-of-the-art research...