Introduction.- Phage display identifies a specific high-affinity binding peptide RE-1 for lanthanide (LN) nanomaterials.- RE-1 forms a stable coating layer on the surface of upconversion nanoparticles / nanocrystals (UCN).- Reduction of UCN sedimentation and nanomaterial-cell interaction by RE-1 coating.- RE-1 coating abrogates autophagy induction and toxicity for UCN in vitro and in vivo.- Enhancement of cell interaction and autophagy induction...
Related Subjects
Engineering Science Science & Math Science & Scientists Science & Technology Technology