Transition-Metal-Free Synthesis of Amines from Nitrosoarenes: C-N Cross-Coupling Reaction of Nitroso Compounds with Boronic Acids

By Silvia Roscales

Aromatic amines are compounds that have found widespread use in medicinal applications and materials science; consequently, their manufacture is one of the fastest-growing sectors in the chemical industry worldwide. The current trend in the industry is cost reduction and environmental compliance (sustainability); for that reason, the demand for new, green, and economic methods for the synthesis of these compounds has been intensified. This book provides a detailed description of a new method for the synthesis of functionalized secondary arylamines starting from nitrosoarenes and boronic acids in the presence of triethyl phosphite under metal-free-conditions. The plethora of research substained in the book will provide a detailed outlook on synthetic applications of this cross-coupling reaction and will open new horizons to extend the methodology development. The operational ease, broad functional group tolerance and scalability of the reaction make it suitable for adoption in both academic and industrial settings. The book should be specially useful to chemists or anyone else who may be interested in the synthesis of amines or in the reactivity of nitrosoarenes or boronic acids.

• Format: Paperback
• Language: English
• ISBN: 6200306427
• ISBN13: 9786200306425
• Release Date: September 2019
• Publisher: LAP Lambert Academic Publishing
• Length: 88 Pages
• Weight: 0.31 lbs.
• Dimensions: 0.2" x 6.0" x 9.0"