This issue of the journal reports regular papers. The ?rst contribution is by ParasChopra and Andreas Bender and discusses quantitative modelling aspects of the bgl operon for E. coli. The second contribution is by Rodrick Wallace and Deborah Wallace and deals with ecosystem transitions a?ecting phenotype - pressions and selection mechanisms. The techniques used are statistical models. The thirdcontributionis byRoberto Barbuti, Andrea Maggiolo-Schettini,...