Katharine Ashley is a dutiful, middle-aged mother of two who experiences sudden heart failure. Thisby Bennet is a rich and skinny young woman whose dangerous taste for drugs and men leads her to an equally untimely death. When, somewhere in the transom between this world and the next, Katharine's wandering soul enters Thisby's body, the story begins - an astonishing tale of reincarnation, regret, and surprising second chances.