Lisbon, 1898: Antonio Maria, surgeon and notorious playboy, returns home after a long absence to learn his beloved father has syphilis, the scourge of both rich and poor. Determined to find a cure, Antonio sets sail for Peking, to study under the evasive but renowned Dr. Xu. But Dr. Xu does not intend to give away his knowledge, and Antonio suddenly falls in love with his assistant, the elusive Fumi. The threat of the advancing Boxer rebellion hangs...