A chance discovery takes anthropologist-turned-novelist Maude Travers through a centuries-old missing person's investigation. Each piece of evidence triggers vivid dreams of the Sloane sisters as they help Buffalo's poorest residents during the cholera epidemic of 1849. Maude is compelled to keep digging as she suspects that her dreams of Martha Sloane and the decisions she struggles with as the first female medical student might, in fact, be true...