The Myc/Max/Mad Transcription Factor Network

by Robert N. Eisenman

Preface.- Making Myc.- Transcriptionsl Activation by the Myc Oncoprotein.- Mechanisms of Transcriptional Repression by Myc.- The Mad Side of the Max Network: Antagonising the Function of Myc and More.- Structural Aspects of Interactions within the Myc/Max/Mad Network.- Myc Target Transcriptomes.- c-Myc, Genome Instability, and Tumorigenesis: The Devil is in the Details .- Lessons Learned from Myc/Max/Mad Knockout Mice.- Myc/Max/Mad in Invertebrates. The Evolution of the Max Network.- The Mix Network: Evidence for a Parallel Max-like Transcriptional Network that Regulates Energy Metabolism.- Subject Index

• Format: Paperback
• Language: English
• ISBN: 3642421415
• ISBN13: 9783642421419
• Release Date: September 2014
• Publisher: Springer
• Length: 282 Pages
• Weight: 0.93 lbs.
• Dimensions: 0.6" x 6.1" x 9.2"