The Molecular Biology of Steroid and Nuclear Hormone Receptors

By Leonard P. Freedman

Book Overview

1. The Role of Heat Shock Proteins in the Regulation of Steroid Receptor Function.- 2. Subcellular and Subnuclear Trafficking of Steroid Receptors.- 3. Structure and Function of the Steroid and Nuclear Receptor Ligand-Binding Domain.- 4. Structure and Function of the Steroid and Nuclear Receptor DNA Binding Domain.- 5. Modulation of Steroid/Nuclear Receptor Dimerization and DNA Binding by Ligands.- 6. Molecular Mechanisms of Nuclear-Receptor-Mediated Transcriptional Activation and Basal Repression.- 7. Transcriptional Cross-Talk by Steroid Hormone Receptors.- 8. Chromatin and Steroid-Receptor-Mediated Transcription.- 9. Regulation of Glucocorticoid and Estrogen Receptor Activity by Phosphorylation.- 10. Monomeric Nuclear Receptors.- 11. Orphan Nuclear Receptors and Their Ligands.

• Format: Hardcover
• Language: English
• ISBN: 0817639527
• ISBN13: 9780817639525
• Release Date: January 1998
• Publisher: Birkhauser
• Length: 340 Pages
• Weight: 1.44 lbs.
• Dimensions: 0.8" x 6.1" x 9.2"