Lois Pritchard, a general practitioner at the Welsh Llangandida Health Centre and part-time staff at her local Genitourinary Medicine (GUM) clinic, is a forty-year-old, divorced, sarcastic smoker who by her own admission is "not very good with relationships." But when her estranged mother makes a dramatic reappearance demanding a liver transplant, Lois has to examine her loyalties and confront some hard decisions both in and out of the surgery...