After a devastating fire at an insane asylum in California, Hook Runyon has been put in charge of security for a train that is to transport the survivors, alongside the head of the asylum, Dr. Baldwin, the attending doctor, taciturn Dr. Helms, and a self-sacrificing nurse named Andrea, to a new location in Oklahoma. Hook hires a motley crew of WW II veterans to help, and they set out for the new destination. But things go awry on the Insane Train,...