The observations made by Paracelsus concerning the dose-effect relationship of poison are generally just as applicable to health- threatening vibration. With regard to kind, intensity, and duration of the vibration, the "dose" is decisive as to whether the conse- quences are detrimental, unmeaningful, or tolerable with respect to health. This law of nature determines the tasks and goals of those whose aim is to safeguard health. Researchers worldwide...