The synthesis of chalcone system -C=C-C=O is relatively easy to prepare, usually highly reactive and are starting point of preparation of various bioactive compounds. This α,β-unsaturated ketones (chalcones) can be synthesized by Claisen-Schmidt condensation of different aromatic aldehydes with ketone and their cyclization with hydrazine hydrate in basic condition. Numerous pyrazoline derivatives have been found to possess considerable biological...