1 The organization of the sphingosine-1-phosphate signaling system Hugh Rosen, M. Germana Sanna, Pedro J. Gonzalez-Cabrera and Edward Roberts# 2 Structural biology of the S1P1 receptor Michael A. Hanson and Robert Peach 3 Chemical and genetic tools to explore S1P biology Stuart M. Cahalan 4 S1P control of endothelial integrity Yuquan Xiong and Timothy Hla 5 Blood, sphingosine-1-phosphate...