After years of personal and professional turmoil, things are finally looking up for Columbus, Ohio, private eye Andy Hayes. As Sick to Death opens, Andy is relishing his new gig: a drama-free, family-friendly stint as a guard at the Columbus Museum of Art. What could be better than regular hours, a steady paycheck, and an attractive coworker who may be just as interested in him as he is in her? Right on schedule, Andy's newfound equilibrium...