What is Saffron? Saffron is a spice derived from the flower of Crocus sativus, commonly known as the "saffron crocus". The vivid crimson stigma and styles, called threads, are collected and dried for use mainly as a seasoning and coloring agent in food. Saffron contains chemicals that might alter mood, kill cancer cells, decrease swelling, and act like antioxidants. What are the Benefits of Saffron? ...