Preface.- I State of the Art in Resuscitation.- 1 Resuscitation science: from the beginning to the present day.- 2 From Experimental and Clinical Evidence to Guidelines.- 3 Trauma Systems and Trauma Care.- II Advances on Cardiopulmonary Resuscitation (CPR) and Defibrillation.- 4 Compression only CPR versus CPR with ventilations.- 5 Defibrillation and Resuscitation.- 6 Amplitude Spectrum Area to predict the success of defibrillation and to guide resuscitation interventions.- 7 The importance of automated external defibrillation implementation programs.- III Optimization of Cardiopulmonary and Cerebral Resuscitation on Sudden Cardiac Death.- 8 Manual vs Mechanical Chest Compression.- 9 Optimized Approach in Cardiocerebral Resuscitation.- 10 Reperfusion Strategies in Sudden Cardiac Arrest.- 11 Extracorporeal Membrane Oxygenation (ECMO) Strategy in Cardiac Arrest.- IV Pharmacological Approach during CPR.- 12 Vasopressors during CPR.- 13 Targeting Mitochondria during CPR.- 14 The Potential Contribution of Corticosteroids to Positive Cardiac Arrest Outcomes.- 15 Pharmacological induction of hypothermia.- V Post Resuscitation Care.- 16 Effectiveness of Hypothermia in Human Cardiac Arrest and Update on the Target Temperature Management Trial.- 17 New Strategies to Improve Outcome After Cardiac Arrest.- 18 New methods to induce localized brain and general hypothermia.- 19 Predicting Outcome of Cardiac Arrest.- VI Combining Physiology, Clinical Outcome, and Ethics.- 20 Circulating Cardiac Biomarkers and Outcome.- 21 Circulatory Shock: Definition, Assessment and Management.- 22 Resuscitation and Ethics.