The International Space Station (ISS) is an unprecedented achievement in global human endeavors to conceive, plan, build, operate, and utilize a research platform in space. As we near completion of the ISS on-orbit assembly, including all Partner laboratories and elements, we now turn to the real multifaceted purpose of the ISS. We will use the ISS as a human-tended laboratory in low-Earth orbit to conduct multidiscipline research and technology development...