Part I: Detection and Quantification of pADPr 1. Quantitation of Poly(ADP-ribose) by Isotope Dilution Mass Spectrometry Tabea Zubel, Rita Martello, Alexander B?rkle, and Aswin Mangerich 2. Quantification of PARP Activity in Human Tissues: Ex Vivo Assays in Blood Cells and Immunohistochemistry in Human Biopsies Eszter M. Horvath, Zsuzsanna K. Zsengell?r, and Csaba Szabo