Drs. Max Coppes and Russell Ware have assembled a team of authoritative authors to review the topic of Pediatric Hematology. This issue of Pediatric Clinics of North America includes articles on Oral Iron Chelators, Hydroxyurea for Sickle Cell Anemia, Changing Demographics of Thalassemia in the US, Vascular Malformations, Thrombosis and Stroke in Childhood, Blood Banking, ITP, Advances in Hemophilia Therapy, and Decision Analysis in Hematology.