Neurofibromatosis Type 1(NF1)

by Johnson Mbabazi

Neurofibromatosis type 1 is a multifaceted autosomal dominant disorder caused by germline mutations in the NF1 tumour suppressor gene. Approximately all people with neurofibromatosis type 1 develop pigmentary lesions and dermal neurofibromas. Some individuals develop skeletal abnormalities (scoliosis, tibial pseudarthrosis and orbital dysplasia), brain tumours (optic pathway gliomas and glioblastoma), peripheral nerve tumours (spinal neurofibromas,...

• Format: Paperback
• Language: English
• ISBN: 1661565794
• ISBN13: 9781661565794
• Release Date: January 2020
• Publisher: Independently Published
• Length: 32 Pages
• Weight: 0.16 lbs.
• Dimensions: 0.1" x 6.0" x 9.0"