Lower extremity disease (LED) is a chronic, disabling disease that negatively influences the quality of life particularly in elderly and diabetic populations. The primary etiologic causes of LED are peripheral vascular disease (PVD) and peripheral neuropathy (PN) and in association with foot deformities may result in disabling complications such as ulcers, gangrene, and amputation. In the early stages of disease, a significant proportion of the population...