Mutational Analysis in Patients with Uveal Melanomas

by Yuehua Mai

There is no standard treatment for the advanced and metastatic uveal melanoma so far, genotypic characterization of uveal melanoma might identify patients who could benefit from a drug-target based approach. In our study, mutations in genes GNAQ and GNA11, BRAF, NRAS, and KIT in primary and matched metastatic uveal melanoma specimens were evaluated. Statistical analysis was carried out to evaluate correlation between mutational status and clinico-pathological...

• Format: Paperback
• Language: English
• ISBN: 3838152867
• ISBN13: 9783838152868
• Release Date: October 2016
• Publisher: Sudwestdeutscher Verlag Fur Hochschulschrifte
• Length: 92 Pages
• Weight: 0.32 lbs.
• Dimensions: 0.2" x 6.0" x 9.0"