Multiple system atrophy is a rare condition of the nervous system that causes gradual damage to nerve cells in the brain and spinal cord and progressive loss of associated functions. It is a member of a class of neurodegenerative diseases known as synucleinopathies that have in common an abnormal accumulation of the alpha-synuclein protein in various parts of the brain. The hallmark of the disease is the widespread inclusions of misfolded alpha-synuclein...