Molecular Evolution: A Phylogenetic Approach

by Roderic D.M. Page and Edward C. Holmes

The study of evolution at the molecular level has given the subject of evolutionary biology a new significance. Phylogenetic 'trees' of gene sequences are a powerful tool for recovering evolutionary relationships among species, and can be used to answer a broad range of evolutionary and ecological questions. They are also beginning to permeate the medical sciences. In this book, the authors approach the study of molecular evolution with the phylogenetic...

• Format: Paperback
• Language: English
• ISBN: 0865428891
• ISBN13: 9780865428898
• Release Date: January 1998
• Publisher: Wiley-Blackwell
• Length: 352 Pages
• Weight: 1.79 lbs.
• Dimensions: 0.8" x 6.8" x 9.7"

Customer Reviews

Reference I had to have

My graduate advisor handed me his copy of the book and advised that I read Chapter 3. I read the chapter a couple of times, but I was reluctant to give the book back. I found it an invaluable reference on more than one term paper or thesis proposal. I had to have my own copy to avoid any potential chiding he may have given. The book is both informative and readable, doing a good job of explaining the material.

Good overview of molecular evolution studies but a bit outdated

If you're not familiar with DNA sequences analysis and inferring phylogenies, this book is a must read (as far as I know the only introduction book to the field). But it's a bit outdated (Bayesian analysis not covered).

Nice figures

I'm new to molecular evolution and have been confused with various terms and concepts (e.g., cladogram vs. phylogram vs. dendrogram, plesiomorphy vs. apomorphy vs. autapomorphy vs. synapomorphy vs. homoplasy, etc.). Reading other books that try to explain these concepts mostly in words only added more confusion.Every page in this book contains highly illustrative figures that accompanies well written text. Of course, not all sections are not immediately clear to understand, and I would need to read other books as well.If you are new to molecular evolution, start with this book along with any other books that may suit your particular need.

Trees and more trees

Although molecular phylogenetic analysis can be extremely complex, this reference provides an introduction to the subject that is straightforward to read. The reference begins with consideration of trees, which are structures used to model actual evolutionary relationships between genes or entire lifeforms. It then provides an introduction to molecular and population genetics. Coding as well as noncoding DNA (tandem repeats, transposable elements, retroviruses, spacer DNA) is considered. The reference then considers how genetic change can be measured, followed by how we can deduce molecular phylogenies. The validity of the molecular clock is then considered, along with a discussion of the neutralist-selectionist debate. The reference finally considers how different phylogenies can be combined to determine actual phylogeny, reconciled trees, and rates of diversification.

Handy read

This book is very well written and a handy tool for anyone who is new to molecular evolution. Nice diagrams and concise chapters. The authors know how to break up the sometimes demanding ideas into appropriate bites. Perfect for grad students and senior undergrads.