Modeling of Kinases Inhibitors: 3D-QSAR, Moecular Docking and ADMET

by Adnane Aouidate

The human kinome contains 518 proteins. They share a common mechanism of protein phosphorylation known to play an important role in cellular signaling pathways. Impaired kinase function is recognized to be involved in severe diseases like cancer. The challenge of this PhD work is the in silico identification of potentially interesting molecules concerning the inhibitory process of a set of protein kinases, namely PIM1, PIM2, CDC7, DRAK2 and CAMKIIδ...

• Format: Paperback
• Language: English
• ISBN: 6202789360
• ISBN13: 9786202789363
• Release Date: September 2020
• Publisher: Noor Publishing
• Length: 144 Pages
• Weight: 0.49 lbs.
• Dimensions: 0.3" x 6.0" x 9.0"