Microarrays for an Integrative Genomics

by Atul J. Butte, Isaac S. Kohane, Alvin Kho, et al.

Book Overview

Functional genomics - the destruction of the genome to determine the biological function of genes and gene interactions -is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level.

• Format: Hardcover
• Language: English
• ISBN: 026211271X
• ISBN13: 9780262112710
• Release Date: August 2002
• Publisher: Bradford Book
• Length: 306 Pages
• Weight: 2.10 lbs.
• Dimensions: 0.8" x 7.2" x 9.4"

Customer Reviews

Well written

This is a well written book that gives an overview of the technology of microarrays and their use as investigative tools in functional genomics experiments. I found the technical and analytical descriptions very easy to follow. This is still the only book around that can bring any investigator with little knowledge of molecular biology, data analysis, and/or microarrays up to speed in the field. It is also a good text book for a graduate level course on microarray data analysis.

Amazing

This is the book we have all been waiting for. The authors do an amazing job of describing, in understandable terms, how to perform meaningful microarray experiments. I highly recommend this seminal work.

The masters' secrets unveiled

This book is an excellent educational source for the rapidly exploding field of bioinformatics, particularly in the area of functional genomics- i.e. teasing out the functions of the thousands of genes in the genome. Described in clear detail are many approaches to the complex analysis of RNA expression array data, including the appropriate situations for use and advantages and pitfalls inherent in each approach. The reader will learn biological theory integrated with mathematical concepts. The authors also clearly have a lucid understanding of the technical strengths and weaknesses of microarray technology.

Pragmatic, candid, useful advice from the pioneers

The data miners have arrived and are pitching camp around the genomic wellsprings of data opened up by DNA microarrays. To extract the good stuff, however, experiments must be designed and analyzed with care.This book gathers the pragmatic, candid, useful advice from the pioneers that you'll want to have if you want to join them.

they told us the Human Genome was finished...

... but they didn't tell us that nobody knew what it meant. Reading this book is a good first step toward understanding the next 30 years of genetics research.