Regulators and Effectors of Small Gtpases: Ras Family: Volume 407

by Alan Hall

The Ras superfamily (>150 human members) encompasses Ras GTPases involved in cell proliferation, Rho GTPases involved in regulating the cytoskeleton, Rab GTPases involved in membrane targeting/fusion and a group of GTPases including Sar1, Arf, Arl and dynamin involved in vesicle budding/fission. These GTPases act as molecular switches and their activities are controlled by a large number of regulatory molecules that affect either GTP loading (guanine...

• Format: Hardcover
• Language: English
• ISBN: 0121828123
• ISBN13: 9780121828127
• Release Date: April 2006
• Publisher: Academic Press
• Length: 824 Pages
• Weight: 2.75 lbs.
• Dimensions: 1.3" x 6.6" x 9.2"