This issue of Sleep Medicine Clinics focuses on Medications and their Effects on Sleep and Wake, with topics including: Sleep-wake neurochemistry; Effect of sleep and circadian rhythm on pharmacokinetics and pharmacodynamics; Drugs used in insomnia and non restorative sleep; Drug-induced excessive sleepiness; Drug-induced insomnia; Drug-induced sleep disordered breathing and ventilatory impairment; Drug-induced parasomnias and movement disorders;...