This volume collects the accepted papers presented at the Learning and Intelligent OptimizatioN conference (LION 2007 II) held December 8-12, 2007, in Trento, Italy. The motivation for the meeting is related to the current explosion in the number and variety of heuristic algorithms for hard optimization problems, which raises - merous interesting and challenging issues. Practitioners are confronted with the b- den of selecting the most appropriate...