Immunobiology of Bacterial Cpg-DNA

by H. Wagner

Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules and pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book is the first comprehensive...

• Format: Paperback
• Language: English
• ISBN: 364264077X
• ISBN13: 9783642640773
• Release Date: September 2011
• Publisher: Springer
• Length: 246 Pages
• Weight: 0.82 lbs.
• Dimensions: 0.6" x 6.1" x 9.2"