Hydrolysis in Drug and Prodrug Metabolism

by Bernard Testa and Joachim M. Mayer

Many drugs and other xenobiotics (e.g., preservatives, insecticides, and plastifiers) contain hydrolyzable moieties such as ester or amide groups. In biological media, such foreign compounds are, therefore, important substrates for hydrolytic reactions catalyzed by hydrolases or proceeding non-enzymatically. Despite their significance, until now, no book has been dedicated to hydrolysis and hydrolases in the metabolism of drugs and other xenobiotics...

• Format: Hardcover
• Language: English
• ISBN: 390639025X
• ISBN13: 9783906390253
• Release Date: August 2003
• Publisher: Wiley-Vch
• Length: 800 Pages
• Weight: 4.45 lbs.
• Dimensions: 1.7" x 7.2" x 9.8"