Hyaluronan in Cancer Biology

by Robert Stern

Hyaluronan biology is being recognized as an important regulator of cancer progression. Paradoxically, both hyaluronan (HA) and hyaluronidases, the enzymes that eliminate HA, have also been correlated with cancer progression. Hyaluronan, a long-chain polymer of the extracellular matrix, opens up tissue spaces through which cancer cells move and metastasize. It also confers motility upon cells through interactions of cell-surface HA with the cytoskeleton...

• Format: Hardcover
• Language: English
• ISBN: 0123741785
• ISBN13: 9780123741783
• Release Date: April 2009
• Publisher: Academic Press
• Length: 468 Pages
• Weight: 1.85 lbs.
• Dimensions: 1.1" x 6.1" x 9.1"