Group Sequential Methods with Applications to Clinical Trials

by Christopher Jennison and Bruce W. Turnbull

Group sequential methods answer the needs of clinical trial monitoring committees who must assess the data available at an interim analysis. These interim results may provide grounds for terminating the study-effectively reducing costs-or may benefit the general patient population by allowing early dissemination of its findings. Group sequential methods provide a means to balance the ethical and financial advantages of stopping a study early against...

• Format: Hardcover
• Language: English
• ISBN: 0849303168
• ISBN13: 9780849303166
• Release Date: September 1999
• Publisher: CRC Press
• Length: 410 Pages
• Weight: 1.15 lbs.
• Dimensions: 1.1" x 6.5" x 9.6"