Gastrointestinal Stromal Tumors

by Dorra Aloui and Sarra Ben Rejeb

The molecular alterations most frequently associated with GIST are mutations in the KIT and PDGFRA genes. Many other genetic abnormalities have been described, such as amplification of C-MYC, MDM2, EGFR1 and CCND1. The objective of this study was to analyze by immunohistochemical method the prognostic value of C-MYC and EGFR overexpression in GIST. We retrospectively collected 25 cases of GIST diagnosed in our department over a period of 15 years...

• Format: Paperback
• Language: English
• ISBN: 6207145518
• ISBN13: 9786207145515
• Release Date: February 2024
• Publisher: Our Knowledge Publishing
• Length: 100 Pages
• Weight: 0.35 lbs.
• Dimensions: 0.2" x 6.0" x 9.0"