G-Quadruplex DNA: Methods and Protocols

Book Overview

Recent work has revealed that stabilizing G-quadruplexes in telomeric DNA inhibits telomerase activity, providing impetus for the development of G-quartet-interacting drugs, while G-quartet-containing oligonucleotides have been recognized as a potent class of aptamers effective against STAT3 and other transcription factors implicated in oncogenesis, proving these guanine-quartets to be a vital and rich area for future study. In "G-Quadruplex DNA:...

• Format: Hardcover
• Language: English
• ISBN: 1588299503
• ISBN13: 9781588299505
• Release Date: December 2009
• Publisher: Humana
• Length: 276 Pages
• Weight: 1.50 lbs.
• Dimensions: 0.9" x 7.2" x 9.8"