Formulating Poorly Water Soluble Drugs

By Robert O. Williams III

Book Overview

Route-Specific Challenges in Delivery of Poorly Water Soluble Drugs.- Optimizing the Formulation of Poorly Water Soluble Drugs.- Solid-State Techniques for Improving Solubility.- Mechanical Particle Size Reduction Techniques.- Solubilized Formulations.- Injectable Formulations of Poorly Water Soluble Drugs.- Design and Development of Self-Emulsifying Lipid Formulations for Improving Oral Bioavailability of Poorly Water-Soluble and Lipophilic Drugs.- Structured Development Approach for Amorphous Systems.- Melt Extrusion.- Spray Drying Technology.- Pharmaceutical Cryogenic Technologies.- Precipitation Technologies for Nanoparticle Production.- Emerging Technologies to Increase the Bioavailability of Poorly Water Soluble Drugs.- Regulatory Considerations for Development and Commercialization of Poorly Water Soluble Drugs.

• Format: Paperback
• Language: English
• ISBN: 3319826182
• ISBN13: 9783319826189
• Release Date: July 2018
• Publisher: Springer
• Length: 779 Pages
• Weight: 2.41 lbs.
• Dimensions: 1.6" x 6.1" x 9.2"