Now in two-colour throughout, the fourth edition of Eukaryotic Transcription Factors has been completely rewritten and restructured to take into account the tremendous advances in our understanding of transcription factors and the mechanisms by which they act. Considerable emphasis has been given to the interaction between transcription factors and chromatin structure. Also included is an entirely new section on the mediator complex and expansion of the space devoted to co-activators and co-repressors.This book is essential reading for all those who wish to understand the impact of molecular biology on medicine, whatever their speciality.
I read this book in a semester in a biochem special topics class. The explanations are pretty good, although some are a little confusing and need to be reworded. It was very nice having a book on one subject. Other texts might need to be referenced, especially for Chapter 2 - some of the ways to get transcription factors - cDNA, etc. The pictures, although simple, are very helpful in understanding the concepts. Beware of the last chapter though. A bunch of transcription factors are thrown at you at once. That was a lot to digest in a short amount of time.
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