Dynemicin A, Uncialamycin and Analogues

by Mickael Jean, Pierre Van De Weghe, Daniel Best

Enediynes are natural products with highly active cytotoxicity and antibacterial activity, and thus have significant potential in the development of anti-cancer treatments. However, they are not readily available and can degrade rapidly during isolation; one solution is to produce them using total synthesis.Dynemicin A and uncialamycin are two such enediynes, with similar structures, for which total synthesis has been achieved. This book presents...

• Format: Hardcover
• Language: English
• ISBN: 1785481509
• ISBN13: 9781785481505
• Release Date: June 2016
• Publisher: Iste Press - Elsevier
• Length: 144 Pages
• Weight: 0.85 lbs.
• Dimensions: 0.5" x 6.0" x 9.0"