Drug-Like Properties: Concepts, Structure Design and Methods from Adme to Toxicity Optimization

by Edward H Kerns, Li Di, Edward H. Kerns, et al.

Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will successfully complete human Phase I clinical trials. Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization, Second...

• Format: Hardcover
• Language: English
• ISBN: 0128010762
• ISBN13: 9780128010761
• Release Date: January 2016
• Publisher: Academic Press
• Length: 580 Pages
• Weight: 3.90 lbs.
• Dimensions: 1.3" x 8.6" x 10.9"