John Madison Darwin is a stand-up guy. He's in his early thirties, and the ennui and apathy of his moderate-success as a government statistician has caught up with him. After a (disappointingly anticlimactic) breakup with his longtime girlfriend while writing an aimless parody of a popular poem, he decides to embark on a journey to fulfill his lifelong dream: to appear as a guest on his favorite comedy news program. In order to do this, he sets out...