Computing Characterizations of Drugs for Ion Channels and Receptors Using Markov Models

by Aslak Tveito and Glenn Lines

Book Overview

Flow of ions through voltage gated channels can be represented theoretically using stochastic differential equations where the gating mechanism is represented by a Markov model. The flow through a channel can be manipulated using various drugs, and the effect of a given drug can be reflected by changing the Markov model. These lecture notes provide an accessible introduction to the mathematical methods needed to deal with these models. They emphasize...

• Format: Paperback
• Language: English
• ISBN: 3319807080
• ISBN13: 9783319807089
• Release Date: April 2018
• Publisher: Springer
• Length: 261 Pages
• Weight: 0.90 lbs.
• Dimensions: 0.6" x 6.1" x 9.2"