This book constitutes the refereed proceedings of the 18th International Conference on Computer Aided Verification, CAV 2006, held as part of the 4th Federated Logic Conference, FLoC 2006. Presents 35 revised full papers together with 10 tool papers and 4 invited papers adressing all current issues in computer aided verification and model checking - from foundational and methodological issues ranging to the evaluation of major tools and systems