Quantitative Relations Among Temperature, Analyte Concentration in Solution, Stochastic Dynamic Diffusions and Mass Spectometric Variable Intensity

By Richard Hamming

Book Overview

Academic Paper from the year 2020 in the subject Chemistry - Analytical Chemistry, grade: Second author Michael Spiteller, University of Dortmund (Institut f r Umweltforschung), language: English, abstract: The idea for this contribution has its root in exact formulas connecting between measurable variable intensity of mass spectrometric peak of analyte ion and its stochastic dynamic diffusion parameter introduced, more recently in our works devoted to quantitative mass spectrometry. Herein, we present innovative functional relations connecting among not only DSD- and I-parameters, but also the experimental factor temperature and the concentration of analyte in solution. The temperature is one of the most important parameter determining the ionization efficiency of analytes under soft-ionization mass spectrometric conditions. The focus of the work is not only on outlining quantitative conjunctions among experimental factors, respectively, parameters; measurable outcomes; and molecular properties, but also to help readers achieve in-depth understanding of governing factors determining the ionization efficiency of analyte ions with respect to temperature at a molecular level. Another important aspect for studying is that, all theoretical proposals introduced, so far, are based on stochastic dynamics. The latter field, however, is very broad. It encompasses a large set of mathematical methods applicable to explain diverse phenomena not only in the Chemistry, but also in the Physics, Astronomy, Economy, and many more research areas. The methodology used to our principle theory behind the derivation of model functional relations; our innovative empirical modification of known relationship; and corresponding definition of the DSD parameter as a function of the measurable variable intensity are based on Box-M ller method, Einstein's concept of diffusion within his molecular kinetic theory of heat; the forward Fokker-Planck equation (or the forward Kolmogorov equation, )

• Format: Paperback
• Language: English
• ISBN: 3346124401
• ISBN13: 9783346124401
• Release Date: March 2020
• Publisher: Grin Verlag
• Length: 278 Pages
• Weight: 0.81 lbs.
• Dimensions: 0.6" x 5.8" x 8.3"