Chromatin: Structure and Function

by Alan P. Wolffe

Book Overview

Provides a concise and coherent account of the nature, structure and assembly of chromatin and its involvement in the processes of DNA transcription, replication and repair. The book constantly... This description may be from another edition of this product.

• Format: Paperback
• Language: English
• ISBN: 0127619151
• ISBN13: 9780127619156
• Release Date: April 1999
• Publisher: Academic Press
• Length: 456 Pages
• Weight: 1.75 lbs.
• Dimensions: 0.8" x 6.1" x 9.0"

Customer Reviews

Chromatin Structure and Function:

Overall this is a good book, considering the fact that chromatin structure and function is such a broad subject. It is very comprehensive, and I liked that about it. It has a definite bias in favour of chromatin STRUCTURE rather than function. It tends to deal mainly with chromatin at the molecular level rather than at the chromosome level. I would have preferred more information about chromosomes, centromeres, telomeres, and position effects. But the book is certainly not lacking on information about chromatin organization proteins and transcription factors. One drawback for me personally was the way the book was organized. It is not organized into bedtime reading 'bite-sized' CHAPTERS the way I like my books to be. It is instead organized into one long monologue, punctuated only by subsections (subsection 1.2.1.1, subsection 2.1.1.1...etc. as if we don't get enough of that in research papers!). The book tends to be a bit DULL for my taste, but it is certainly a good way to get 'up to speed' in the chromatin field. Greg Doheny (Vancouver B.C.)

well written and up to date

In a fast-moving field such as chromatin structure and function, one is usually better off reading journal articles than trying to gain a background by reading a text. This is not the case with Dr. Wolffe's book, Chromatin: Structure and Function. The book covers the background and then forges into new and interesting data. I was required to buy this book for a class, and was originally resentful of the cost, but now I keep it in lab and find myself consulting it every once in a while. The explanations are clear, the diagrammes informative, and the science is good.