Calculation of Drug Lipophilicity: The Hydrophobic Fragmental Constant Approach

by Raimund Mannhold and Roelof F. Rekker

Comprehensive and comparative, this 'cookbook' gives the ingredients and recipes for setting up lipophilicity calculations of a great variety of organic molecules. Of particular interest is the extended presentation of the yet unpublished, revised version of the Sigma f-lipophilicity calculation procedure (REKKER-system). Calculation examples of 36 drugs familiarize the user quickly with the calculation method and allow a comparative quality proof...

• Format: Hardcover
• Language: English
• ISBN: 3527284222
• ISBN13: 9783527284221
• Release Date: January 1992
• Publisher: Wiley-Blackwell
• Length: 113 Pages