Biomedical Informatics for Cancer Research

by Ramana V. Davuluri, John T. Casagrande, Michael F. Ochs

Book Overview

view, showing that multiple molecular pathways must be affected for cancer to develop, but with different specific proteins in each pathway mutated or differentially expressed in a given tumor (The Cancer Genome Atlas Research Network 2008; Parsons et al. 2008). Different studies demonstrated that while widespread mutations exist in cancer, not all mutations drive cancer development (Lin et al. 2007). This suggests a need to target only a deleterious...

• Format: Paperback
• Language: English
• ISBN: 1489984518
• ISBN13: 9781489984517
• Release Date: November 2014
• Publisher: Springer
• Length: 354 Pages
• Weight: 1.15 lbs.
• Dimensions: 0.8" x 6.1" x 9.2"