Biomedical Applications of Acridines: Derivatives, Syntheses, Properties and Biological Activities with a Focus on Neurodegenerative Diseases

by Jaroslav Sebestik, Jan Hlavaček, Jan Jezek

Book Overview

Describes modern and conventional syntheses of acridine scaffolds

Presents structural aspects of interactions with proteins which provide useful tips for designing enzyme inhibitors involved in the treatment of neurodegenerative diseases

Discusses structural aspects of interactions with nucleic acids, which helps readers to design a specific binder for the targeting of quadruplexes involved in cancer

• Format: Hardcover
• Language: English
• ISBN: 3319639528
• ISBN13: 9783319639529
• Release Date: August 2017
• Publisher: Springer
• Length: 237 Pages
• Weight: 1.17 lbs.
• Dimensions: 0.6" x 6.1" x 9.2"