Bioisosteres in Medicinal Chemistry

by Nathan Brown

Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes...

• Format: Hardcover
• Language: English
• ISBN: 3527330151
• ISBN13: 9783527330157
• Release Date: October 2012
• Publisher: Wiley-Vch
• Length: 256 Pages
• Weight: 0.40 lbs.
• Dimensions: 0.7" x 6.9" x 9.7"