Binding and Linkage: Functional Chemistry of Biological Macromolecules

by Jeffries Wyman and Stanley J. Gill

Book Overview

This university-level classic text reference by Wyman and Gill is the standard go-to reference in the area of thermodynamic linkage with respect to biological macromolecules. This description may be from another edition of this product.

• Format: Hardcover
• Language: English
• ISBN: 0935702563
• ISBN13: 9780935702569
• Release Date: January 1990
• Publisher: University Science Books
• Length: 330 Pages
• Weight: 1.50 lbs.
• Dimensions: 0.9" x 6.8" x 9.6"

Customer Reviews

Great for Calculating Binding Curves etc.

I am a biophysicist and used this book to derive binding curves as part of my PhD thesis research. Wyman and Gill present their work in a understandable and clear fashion. The book is largely based off of the papers published by Gill and De Cera over a ten year period, but it shows their work in a general and flowing manner-which you would not get if you just read all the papers seperately. Each section references all the corresponding papers, so you can get more detail on any given topic. While combing through the book, I noticed some very small errors with some equations (typo -wrong symbol) or with some references (wrong paper citated, not applicable). But generally if you follow along the derivation of any binding polynomials he presents, you can catch the little errors. Altogether a wonderful resource that educates you in how to derive a binding curve for hemoglobin and other macro molecules, given certain conditions and restraints.